Diabetes

When your diabetes start to damage your heart

Your diabetes may start to damage your heart in very initial phases of your diabetes, even in prediabetes phase.this damage to heart can be devided in different phases.

Phase 1:

The Invisible Start (Years Before Diagnosis)Heart damage actually begins during insulin resistance, which can occur 5 to 10 years before a person is ever diagnosed with type 2 diabetes.Infact this prediabetes phase is because of insulin resistance, that causes high insulin levels in you blood that trigers inflammation.That causes your kidneys to retain extra sodium, quietly creeping your blood pressure upward.Moreover this prolonged inflammation may damage blood vessel lining.Also alter your liver function, lowering your “good” HDL cholesterol and raising dangerous triglycerides.By the time someone is told they have prediabetes, early stages of blood vessel stiffening are often already underway.

Phase 2:

When your blood sugar finally rises enough to cross into the prediabetes category (an HbA1c between 5.7% and 6.4%), the damage accelerates.At this point, frequent post-meal blood sugar spikes create cellular waste products called Advanced Glycation End-products (AGEs). These molecules act like micro-scratches on the smooth, internal lining of your blood vessels.Your body tries to heal these scratches using cholesterol, which inadvertently kicks off the process of plaque buildup (atherosclerosis).

 

Phase 3:

When the fasting blood sugar passes 126 mg/dL or your HbA1c reaches 6.5%, type 2 diabetes is fully established.High glucose levels begin damaging the microscopic blood vessels that supply oxygen directly to your heart muscle and your autonomic nervous system.Over a timeline of 5 to 15 years of unmanaged diabetes, this combined damage can lead to:Diabetic Cardiomyopathy.
A positive thing is that the endothelial lining of your blood vessels has the ability to heal up, if rate of damaging ramains less then healing rate.

Dr. R.A Khan

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